SAQ 582 – Toxicology – ethylene glycol ingestion with metabolic acidosis

A 42-year-old man is brought to the emergency department after ingesting 200 mL of antifreeze. He is drowsy with slurred speech. His observations and initial blood results are shown below.

Observation	Result
Heart rate	110/min
Blood pressure	130/75 mmHg
Respiratory rate	24/min
SpO2	95% room air

Parameter	Result	Reference range
pH	7.21	7.35-7.45
pCO2	24	35-45
HCO3	6	24-32
Sodium	140	135-145
Potassium	3.9	3.5-5.0
Chloride	100	95-110
Glucose	5
Ethanol	Undetectable
Urea	5	3-8
Osmolality	330	275-295

Provide two (2) calculations to help interpret these results.

(Marked out of 2.0)
</p> <table class="saq-prop-table"> <thead> <tr> <th>Derived value</th> <th>Calculation or result</th> </tr> </thead> <tbody> <tr> <td>1.</td> <td></td> </tr> <tr> <td>2.</td> <td></td> </tr> </tbody> </table> <p>

/ 2

List three (3) possible life-threatening features of this poisoning.

(Marked out of 3.0)

/ 3

What is the role of decontamination in this poisoning?

(Marked out of 1.0)

/ 1

List three (3) key management steps and give one (1) justification for each.

(Marked out of 6.0)
</p> <table class="saq-prop-table"> <thead> <tr> <th>Management step</th> <th>Justification</th> </tr> </thead> <tbody> <tr> <td>1.</td> <td></td> </tr> <tr> <td>2.</td> <td></td> </tr> <tr> <td>3.</td> <td></td> </tr> </tbody> </table> <p>

/ 6

Total Score: 0 / 12

Percentage: 0%