SAQ 1149 – Overdose with high anion gap acidosis

Marked out of 22.00

A 23-year-old man presents to a rural ED after possible overdose and self-harm risk. His blood glucose is normal and the point-of-care venous blood gas is shown below.

Test Result Reference range
pH 7.34 7.35-7.45
Bicarbonate 16 mmol/L 22-28
Base excess -6 -2 to 2
pO2 105 mmHg 80-110
pCO2 31 mmHg 36-45
Lactate 9.6 mmol/L <2
Na 136 mmol/L 135-145
Cl 104 mmol/L 95-110
K 4.2 mmol/L 3.2-5.0

State two (2) primary acid-base abnormalities on this blood gas.

(Marked out of 2.0)


/ 2

State the calculation for the expected CO2.

(Marked out of 1.0)


/ 1

State the three (3) most likely causes of the abnormal results.

(Marked out of 3.0)


/ 3

There is concern about ethylene glycol ingestion. List two (2) blood gas features that are most specific for this toxic alcohol ingestion.

(Marked out of 2.0)


/ 2

List and justify four (4) important investigations in suspected ethylene glycol ingestion.

(Marked out of 8.0)


/ 8

It emerges that he ingested a significant volume of ethylene glycol. List and justify three (3) immediate ED management priorities, including dose and route for medications or fluids.

(Marked out of 6.0)


/ 6

Total Score: 0 / 22

Percentage: 0%