SAQ 347 – Haematology – thrombocytopaenia and TTP

Marked out of 13.00

A junior registrar is assessing a 46-year-old woman with fever, altered mental state, and no clear infectious source. She has received empiric IV flucloxacillin and gentamicin. Her FBC shows Hb 108 g/L, WCC 6.5, and platelets 43.

In ideal circumstances, below what platelet count would you transfuse for lumbar puncture, central venous catheter insertion, and an asymptomatic patient?

(Marked out of 1.5)

Indication Platelet threshold
Lumbar puncture, afebrile
Central venous catheter
Asymptomatic patient


/ 1.5

List the five (5) features of TTP.

(Marked out of 2.5)


/ 2.5

Discuss treatment options for TTP.

(Marked out of 3.0)


/ 3

Complete the comparison table for TTP, DIC, and ITP.

(Marked out of 6.0)

Feature TTP DIC ITP
Platelet count
INR/PT
Microangiopathic haemolytic anaemia
Fibrinogen
Safe to give platelets


/ 6

Total Score: 0 / 13

Percentage: 0%

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